福山臨床検査センター

論文

Helicobacter pylori に対するワクチンの作製とその効果

1)
Ikeda Y., Fujii R., Ogino K., Fukushima K., Hifumi E., Uda T. Immunological features and inhibitory effects on enzymatic activity of monoclonal antibodies against Helicobacter pylori urease. J Ferment Bioeng, 86 (3), 271-276 (1998)
2)
Fujii R., Morihara F., Fukushima K., Oku T., Hifumi E., Uda T. Recombinant antigen from Helicobacter pylori urease as vaccine against H. pylori-associated disease. Biotechnol Bioeng, 86 (7), 737-746 (2004)
3)
Morihara F., Fujii R., Hifumi E., Nishizono A., Uda T. Effects of vaccination by a recombinant antigen ureB138 (a segment of the β-subunit of urease) against Helicobacter pylori infection. J Med Microbiol, 56, 847-853 (2007)
4)
Morihara F., Hifumi E., Yamada M., Nishizono A. Uda T. Therapeutic effects of molecularly designed antigen UREB138 for mice infected with Helicobacter pylori. Biotechnol Bioeng, 100 (4), 634-643 (2008)

プロテオーム解析法による疾病検査システムの開発

1)
木本真史、吉里勝利:「プロテオーム解析の疾病検査への応用」 細胞 34(1), 30-31, (2002)
2)
Saito M., Kimoto M., Araki T., Shimada Y., Fujii R., Oofusa K, Hide M., Usui T., Yoshizato K. Proteome analysis of gelatin-bound urinary proteins from patients with bladder cancers. European Urology, 48, 865-871 (2005)